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You should contact your GP if: You have been found to have elevated B12 levels on blood tests, particularly if levels exceed 1000 ng/L (approximately 740 pmol/L, though laboratory reference ranges vary) and you are not taking high-dose supplements You develop new symptoms after starting B12 supplementation, including persistent skin rashes, significant gastrointestinal disturbance, or unexplained symptoms You have underlying liver disease, kidney problems, or blood disorders and are considering B12 supplementation You are taking B12 supplements without medical supervision and have not had your levels checked, particularly if taking doses exceeding 2000 micrograms daily You experience symptoms that might indicate underlying disease, such as unexplained weight loss, persistent fatigue, jaundice, or abdominal swelling Call 999 or go to A&E if you develop severe allergic reactions following B12 injections, including difficulty breathing, facial swelling, or widespread rash, as these may indicate anaphylaxis, though this is extremely rare

Whether a gluten-free diet should be recommended in chronic autoimmune thyroiditis or not?-A 12-month follow-up

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Characteristics of Human Skin Color The color of human skin is mainly determined by the two types of melanin, the black-brown Eumelanin and the yellow-red pheomelanin Melanogenesis disorders Disturbances of the melanin production pathway lead to the formation of dark or light-colored spots on the skin (pigmentation)

Glutathione is the bodys master detoxifier and the bodys main antioxidant, protecting our cells from damage