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The Lancet 379, 22432251 (2012)
In addition, abdominal discomfort and indigestion are also frequently observed, especially when starting the medication or when increasing the dosage
Minor improvements in digestion or energy may appear within the first week, but noticeable changes in inflammation or mood usually take 48 weeks
Whilst there is no confirmed causal link between retatrutide and serious cardiac events based on current data, the drug's pharmacological profile means that certain symptoms should never be ignored
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