Compounded Medication Notice
Antioxid Redox Signal 38:599618 Che X, Brydges CR, Yu Y, Price A, Joshi S, Roy A, Lee B, Barupal DK, Cheng A, Palmer DM, Levine S, Peterson DL, Vernon SD, Bateman L, Hornig M, Montoya JG, Komaroff AL, Fiehn O, Lipkin WI (2022) Evidence for peroxisomal dysfunction and dysregulation of the CDP-choline pathway in myalgic encephalomyelitis/chronic fatigue syndrome
Important caveat: for OA and PsA, much of the benefit could still be secondary to weight loss itself
It has shown promise as a treatment of erectile dysfunction and autism, among other conditions
Clinical pharmacology studies show tirzepatide has a half-life of approximately 5 days, allowing for once-weekly dosing with sustained therapeutic effects (Frias et al., Diabetes Care, 2021)