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This is the first key shift in perspective: GLP-1 medications are system-level metabolic therapies, not simply appetite suppressants

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There is no single timeline for everyone

Furthermore, given that we have demonstrated that this mitochondrial adaptation is to promote rebalancing of pyrimidine levels, mitochondrial biogenesis could also be used to identify patient cohorts likely to benefit from UCK2 inhibitor combinations

It achieves remarkable efficacy, with trials showing up to a 20.9% body weight reduction