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The FDA has specifically flagged risks including dosing errors, variable concentrations, improper storage during shipping, quality control differences, limited adverse-event reporting, and products falsely marketed for research or non-human-use purposes
Front Med 9:813083 Malewiak MI, Griglio S, Kalopissis AD, Le Liepvre X (1983) Oleate metabolism in isolated hepatocytes from lean and obese Zucker rats
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And overwhelmingly, these drugs have only been available for people who have wealth. (Obesity rates actually are slightly higher for middle-income Americans than they are for those with the lowest and highest incomes, according to 2017-2020 data collected by the US Centers for Disease Control and Prevention.) Kennedy had previously expressed skepticism about GLP-1s, but he was full of praise for Trump for pushing to help a broader segment of Americans have access to the drug
Saxenda is taken at a higher dose and approved for weight loss
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