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After decades with no disease-modifying drug, 20242026 finally delivered the first targeted therapies: Novartis ianalumab met both NEPTUNUS-1 & NEPTUNUS-2 Phase 3 endpoints and won FDA Breakthrough Therapy status in Jan 2026, and J&Js nipocalimab was positive in the Phase 2 DAHLIAS trial ( The Lancet )

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Rare observations of copper uglies: This term, sometimes used in research communities, refers to a potential temporary accelerated aging appearance

It supports the repair process on a cellular level, which can be a game-changer for recovery