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The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher
Starting with lower combination doses and escalating gradually enables individual response assessment before reaching full protocol doses
Patience during apparent stalls distinguishes successful outcomes from premature discontinuation
AOD-9604 is administered via subcutaneous injection into fatty tissue, with the abdominal region being the preferred site
BAC water is pH-adjusted and isotonic, providing an optimal reconstitution environment for the majority of peptide compounds Standard laboratory practice BAC water is the most widely used reconstitution vehicle in peptide research protocols
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