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In clinical trials, the doses of semaglutide provided by Wegovy were associated with an average weight loss of 14.9% of initial body weight and losses of at least 5% in 86.4% of participants over a period of 68 weeks
Patients with high-sensitivity GLP-1 variants may experience nausea within 12 hours, while low-sensitivity variants might not feel effects until day 2 or 3
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