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By inhibiting NNMT, 5-Amino-1MQ increases cellular SAM and NAD+ levels, enhances NAD+ salvage pathway flux, activates SIRT-1, boosts oxidative phosphorylation (OXPHOS), and influences cellular energy homeostasis and epigenetic modifications
Summary: Vitamin B12 deficiency anaemia is a condition where insufficient vitamin B12 prevents production of adequate healthy red blood cells, causing fatigue, weakness, and potentially irreversible neurological damage if untreated
It helps in the production of DNA and RNA, supports the health of nerve cells, and aids in the creation of red blood cells
Untreated vitamin B12 deficiency can lead to anemia or irreversible nerve damage
These findings suggest AOD-9604 may be of interest in research not only for addressing existing damage, but also in the context of prevention
