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The SELECT trial, as noted earlier, went a step further it tested Wegovy in overweight/obese individuals with cardiovascular disease (but without diabetes) and found a 20% reduction in heart attacks, stroke, or CV death ( [67] )

Learn what to do after a denial If Denied, Appeals Often Succeed 65%+ of prior authorization appeals succeed when patients appeal with proper documentation

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Overweight or obesity (BMI 30-plus, or 27-plus with a weight-related condition) where weight loss is the goal and there is no diabetes driving the choice

Although initial findings suggest that GLP-1Ra leads to a slight reduction in bone mineral density and promotes bone remodeling, favoring resorption similar to calorie restriction effects, further research is needed to explore the effects of GLP-1Ra on bone metabolism and fracture-related outcomes, as well as dual- and triple-receptor agonists of GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon in PwO