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, Nat Commun , 2014;5:4113 Kannt A et al

Potency: In preclinical studies, Dihexa was found to be up to one million times more potent than BDNF in promoting synaptic connectivity highlighting its potential but also raising concerns about overstimulation

These drugs effectively lower blood glucose levels and provide cardiovascular and renal benefits, making them a preferred treatment option in diabetes care

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First, animal safety does not reliably translate to humans species differences in metabolism, immune response, and dosing scale are substantial