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A study showed that butyrate attenuated the expression of P-53 and the neuroinflammation in the brains of HFD-fed mice (126)

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The 20 to 35 years old participants received 200 mg Pycnogenol per day or placebo for 30 days, then switched to the other group for another 30 days

This helps more of it reach the bloodstream compared to regular supplements

PMCID: PMC12075970