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Due to its perceived safety and cost-effectiveness, metformin emerges as a potential candidate for OA management

Diabetes Metab J (2019) 43(6):73343

In a head-to-head study of the two agents sponsored by Eli Lilly, makers of tirzepatide, found a 20.2% weight loss with tirzepatide compared to a 13.7% weight loss with semaglutide

Answer: Most reported side effects are mild and dose-related, including injection-site reactions, transient water retention, and occasional numbness or tingling

Overall, oral glutathione is the lowest barrier to entry and the least invasive option, but with the trade-off of being less effective than those more direct options