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Acknowledgements The authors thank M
In clinical trials, patients achieved weight loss of approximately 15-20% from baseline after 72 weeks, with results varying by dose and whether patients had diabetes
However, weakness in the upper body or legs can eventually compromise stability
Supplements can be risky, based on the type of supplement and the concentration taken, and they may also interfere with certain medications
Importantly, their influence extends to skeletal muscle, where GLP-1 RAs promote glucose uptake via the AMP-activated protein kinase pathway, increase vascular blood flow, and mitigate glucotoxicity, thereby supporting muscle protein synthesis and inhibiting catabolic pathways [14, 15]
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