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Limitations and potential biases of the review Although this review provides a comprehensive synthesis of current evidence on GLP-1 RAs as potential gerotherapeutics, several limitations warrant consideration

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If a plant-derived substance is classified by the US Food and Drug Administration as a pharmaceutical drug, it must undergo rigorous testing before its approved

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Diagnostic translation has likewise been advanced by mitochondria-targeted probes: the 5MEF fluorescent probe demonstrates how mitochondrial accumulation and selective signal enhancement enable earlier, organelle-level detection of pathology