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123 Following promising preclinical findings, several clinical trials have been initiated to evaluate the neuroprotective efficacy of GLP-1RAs in diverse populations, including individuals with diabetes, those at risk of cognitive decline, and patients diagnosed with AD or PD
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Semaglutide data were derived from the SUSTAIN (111, FORTE) and STEP (2, UP-DM) programs, whereas tirzepatide data were obtained from SURPASS (16) and SURMOUNT-2 trials
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