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Reduced nitric oxide (NO) production by endothelial cells leads to vascular dysfunction, further compromising testosterone synthesis and secretion [261,262,263]

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No eating disorder screen, no pregnancy or breastfeeding screen, no validated PHQ or mental-health instrument, no substance use or alcohol screen, no self-reported blood pressure or resting heart rate , and no MEN-2 gate split out from the personal-or-family MTC question

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Several clinical studies showed that oral vitamin E (a powerful antioxidant) slowed the progression of Alzheimers [31]