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While major cardiovascular events have not been linked to the compound in the available literature, some studies have noted transient fluctuations

The vote went against the FDA review team's own written recommendation, and it is not binding

Saxena AR, Gorman DN, Esquejo RM et al (2021) Danuglipron (PF-06882961) in type 2 diabetes: a randomized placebo-controlled multiple ascending-dose phase 1 trial

Because appetite tends to decrease, it can be helpful to pay closer attention to protein, fiber, and hydration

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