difference between sglt2 and glp 1 Combining GLP-1 Receptor Agonists Inhibitors in Type 2 Diabetes Mellitus: A Scoping Review and Expert Insights for Clinical Practice Utilizing the Nominal Group Technique | Diabetes Therapy GLP1 Receptor Agonists vs SGLT2-I

Similarly, in mesangial cells, GLP-1 receptor agonists have been shown to suppress either high-glucose-induced or AGEs-induced pro-fibrotic signalling pathways, including NF-B activation and TGF-1 expression, leading to reduced ECM deposition [60,61], and to suppress their proliferation via AMPK activation [62]

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