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Key findings from the Phase 2 trial included: Dose-dependent weight loss , with greater reductions observed at higher doses Significant improvements in waist circumference , blood pressure , and lipid profiles Reductions in fasting glucose and insulin resistance markers, though the clinical significance of these findings in people with type 2 diabetes requires further investigation Weight loss appeared to continue throughout the 48-week period without a clear plateau at the highest doses Whilst these results are encouraging, it is important to contextualise them appropriately

Many plans consider it medically necessary for weight management

Another practical observation is that many people regain weight once the medication is stopped, suggesting the underlying metabolic drivers may not have been fully addressed

Shen, X

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