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Semaglutide and tirzepatide are available now, while retatrutide remains in trials, so the practical comparison for most patients today is between the two approved options
doi:10.1016/S0140-6736(24)01498-3
doi:10.3803/EnM.2019.34.3.247 Abdullah Bin Ahmed I
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(Explains that compounded medications under Section 503A are exempt from FDA pre-market approval requirements, meaning their safety and efficacy are not evaluated by FDA prior to use)
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