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CSF is bathing and sheathing the brain, protecting it from mechanical stress and contributing to brain homeostasis through constant exchange with brain interstitial fluid ( that sample type from living subjects to analyze CNS-related exposure, transport efficiency across neural barriers or metabolic changes in the brain due to neurodegenerative conditions (Solovyev et al., 2013)

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs