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Neuropsychopharmacology 49 , 10421049 (2024)

Many users report noticeable pain reduction within 3 to 7 days, with significant functional improvements appearing by weeks 2 to 3

These details matter because they influence how treatment is monitored and discussed

3) Some believe these drugs will not see widespread adoption because they are most effective subcutaneously (administered via an autoinjector as pictured here): While a certain subset will always have a phobia of needles, its worth considering the lengths that people have gone to in the past to lose weight (taking pills with tapeworms in them, for example)

This argument-based approach should be implemented as a standard approach to validity for PROMs