semaglutide infographic STEP 1 : Treatment Effect in People with Obesity – My Endo Consult Common And Rare Side Effects

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Key Takeaways Phase 2 retatrutide reduced mean systolic blood pressure by approximately 7-8 mmHg at top doses over 48 weeks Diastolic blood pressure dropped by approximately 2-4 mmHg Placebo arm BP changes were minimal, so the active-versus-placebo gap is real and meaningful The effect tracks with weight loss, suggesting most of the benefit is downstream of weight reduction rather than a direct vascular drug effect Patients on antihypertensive medications often need dose reductions as weight loss progresses to avoid excessive BP drops Direct answer Yes

Last updated 9/2023

Funding The author(s) declare financial support was received for the research and/or publication of this article

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