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It is also injected daily as opposed to weekly, making it less attractive to some patients

Plus, since semaglutide lowers appetite and side effects include digestive issues like nausea, vomiting, and abdominal discomfort, it is not always easy to get the proper nutrients in the diet

Others are used off-label and have strong clinical evidence supporting their use for weight loss

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For many patients, these effects diminish over time as the body adapts, though some individuals experience persistent symptoms throughout treatment