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The efficacy and safety appear to be equivalent between the two methods, even though the interpretation is limited by the small numbers and heterogeneity of selected trials
It is used initially in type 2 diabetes mellitus (T2DM) and obesity management, and is available in subcutaneous injections and oral formulations to give patients and healthcare professionals flexibility in administration
More specifically, the GI issues experienced from semaglutide peak at around 20 weeks of treatment and decrease afterward (3)
However, this participant had a slower dose titration due to their heart failure, so took longer to reach the maximum dose
The two most common types are Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy
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