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The body designed the urinary system to flush itself regularly, and anything that interferes with complete voiding disrupts that protective mechanism
By conducting RNA-seq analysis, SOD activity and malondialdehyde assays in ovaries, as well as ROS staining in oocytes, we revealed that the semaglutide treatment reduced the elevated oxidative stress in ovaries and high ROS levels in oocytes from PPO mice, possibly through activating the PI3K/AKT pathway and improving the state of SOD
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Individual serine mutant GLP-1Rs displayed a tendency towards reduced GLP-1-induced cAMP generation without reaching statistical significance when compared to the WT receptor (Fig
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