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For those tracking the regulatory landscape of these compounds, the FDA reclassification guide and 2026 peptide legality update provide current context on research access and clinical availability

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May help prevent diet-induced obesity and improve metabolic health

DHEA therapy has been reported to be associated with adverse side effects such as growth of body and facial hair (hirsutism), acne, greasy or itchy skin, vaginal discharge, and increased sweating and sweat odor

Some small clinical trials have also shown encouraging results. In terms of alcohol miss-use, one study has shown that low dose semaglutide reduced an individuals number of drinking days