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Some individuals may experience gastrointestinal issues such as nausea or abdominal discomfort

This delayed gastric emptying can lead to harder, less frequent stools, particularly during dose escalation or in individuals with pre-existing bowel concerns

1 Introduction Until recently, the worldwide increase in obesity, characterized by a body mass index (BMI) exceeding 30 kg/m 2 , was widely considered an inevitable trend with limited hope for meaningful advances in pharmacological treatment

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