Serious side effects (rare but important) Stop your medication and contact your healthcare provider immediately if you experience: Severe, persistent abdominal pain that radiates to your back (possible pancreatitis, occurring in less than 1% of patients) Signs of gallbladder problems including intense upper-right abdominal pain, fever, and jaundice (approximately 2 to 3% incidence) Symptoms of allergic reaction including facial swelling, difficulty breathing, or widespread rash (less than 1%) Signs of kidney problems including changes in urine output, swelling in legs or ankles, or unusual fatigue Any thoughts of self-harm (reported in post-marketing surveillance) The B12 advantage for side effect management One theoretical advantage of the compounded B12 formulation is the potential to reduce fatigue and maintain neurological function during aggressive caloric restriction
doi: 10.1038/ni.1878 81 FuWGeMLiJ
It may cause side effects, including pain, heavy vaginal discharge, and infections
Tirzepatide: SURMOUNT-1 (72 Weeks) The SURMOUNT-1 trial enrolled 2,539 adults with obesity (BMI 30) or overweight with comorbidities
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