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Oral supplementation (50150 g daily) may suit dietary deficiency without nerve involvement, but malabsorption cases require injections
Moreover, this trial was conducted at a private practice and published in an alternative medicine journal, again raising concerns about bias
StatPearls [Internet]
A 2022 dose-response RCT (Yi et al., Geroscience) at 300/600/900 mg/day raised NAD+ dose-dependently with no safety issues at 60 days
Youll notice B12 supplements usually exceed the recommended daily intake, with many supplements ranging from 500-2000 mcg
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