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(1) Controlled-Release PHEN/TPM in Severely Obese Adults (EQUIP) trial (obesity without comorbidities), (2) Controlled-Release Phentermine plus Topiramate Combination in Overweight and Obese Adults (CONQUER) trial (obesity with comorbidities), and (3) SEQUEL (2-year extension of CONQUER), were comprised of 7% of older adult participants across the trials, although the upper age limit was 70 [111,112,113]
A comprehensive review on metabolic syndrome
Drug manufacturers have developed dual and triple agonists for the modulation of several metabolic pathways, which are intended to improve blood sugar levels and facilitate weight loss
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