When combined with medications such as sodium-glucose cotransporter-2 (SGLT-2) inhibitors or specific insulin formulations that exhibit complementary effects on weight regulation, combination therapy has the potential to significantly enhance weight loss outcomes and improve body composition in patients with co-morbid type 2 diabetes and obesity
Studies have focused on how these combined actions can impact metabolic markers, body composition, and nutrient use in controlled settings
There are eight different enzymes in the GST family of genes identified by Greek letters: alpha, kappa, mu, omega, pi, sigma, theta, and zeta
doi: 10.1080/21688370.2023.2292461, 125 RichardJ
Some studies have also demonstrated the neuroprotective effect of GLP-1RAs through broader mechanisms