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If you are taking immunosuppressants for an autoimmune condition, adding Ta1 requires careful medical oversight

Bulk RNAseq analysis Reads from RNAseq data were processed using the nf-core/RNAseq v3.17.0 pipeline and the GRCm39 genome assembly 55

Adverse events were coded using Medical Dictionary for Regulatory Activities version 17.0 and summarised descriptively [28]

Interscapular brown adipose tissue was homogenized in Tris-ethylenediaminetetraacetic acid (EDTA) buffer (10 mM Tris and 1 mM EDTA, pH 7.4) with 1% protease inhibitor (Nacalai Tesque, Kyoto, Japan) on ice

Retatrutide may help improve metabolic function by increasing energy use and supporting fat breakdown through its action on the glucagon receptor