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IGF-1 LR3 Research Guide: Mechanism, Pharmacology, Laboratory Use IGF-1 LR3 is a long-acting analogue of insulin-like growth factor 1 with an Arg substitution at position 3 and a 13-amino-acid N-terminal extension

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When to seek medical advice: Persistent or worsening injection site reactions (increasing redness, warmth, or discharge suggesting infection) Severe or persistent headaches Chest pain or palpitations Unexplained muscle weakness or cramps New or worsening neurological symptoms despite treatment Unexpected bleeding or bruising For non-emergency concerns, contact your GP or NHS 111

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