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Tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
However, most providers recommend stopping tirzepatide at least one to two months before attempting conception, with some guidance suggesting up to two months as a conservative buffer
Some studies have reported a benefit in elite endurance athletes with a high energy intake and expenditure
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Warning Thyroid Tumour Risk: Tirzepatide caused thyroid C-cell tumours in animal studies
Murray, president emeritus at the Hastings Center
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