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The treatment is not painful

combined use is speculative and may compound adverse metabolic and gastrointestinal effects with no safety framework to guide dosing

It has been shown to promote sleep in several species, including rabbits, rats, mice, and humans, with varying effects on REM sleep in cats 1

It does not require proof of efficacy in large trials the way we typically expect from drugs, but it facilitates prescribing, and that changes things a lot, because there wont be a black market anymore

Keep vials sealed until ready for reconstitution, and allow refrigerated or frozen vials to reach room temperature before opening to minimize condensation