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Most adults tolerate them well

Another factor that can increase the risk of a B12 deficiency is a lack of a diverse diet, says Emily Peron, associate professor in the department of pharmacotherapy and outcomes science at Virginia Commonwealth University

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Mild dermatitis was reported in approximately 10% of sensitive individuals, but no serious adverse effects occurred, supporting the safety of shiitake-based functional foods for lipid management

It is not a guaranteed sleep solution, not a replacement for insomnia treatment, and not something patients should buy online and inject on their own