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Absorption rates can vary based on several factors, such as: The physical properties of the drug (e.g., size and shape of the molecules) The presence of other food or beverages in the stomach or intestines The specific conditions of the stomach at the time of ingestion (e.g., pH level, which measures acidity) If something interferes with medication absorption, the drug may not work as effectively or may take longer to take effect

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A 2024 study from the University of Alberta found that semaglutide also shrank heart muscle in mice, though no harmful effects on heart function were observed