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Regeneration of GSH from GSSG is catalyzed by glutathione reductase (GR), which uses NADPH as an electron donor

The human safety profile of either substance is unknown

Jardiance is a member of a class of medications known as sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors), which control day-to-day blood sugar by reducing the reabsorption of filtered glucose in the kidneys, resulting in increased urinary excretion of glucose and lowered blood sugar concentrations

The animals were divided into three main groups defined as follows: MCAO + Vehicle included animals subjected to MCAO and treated with vehicle (saline)

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