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In addition to the striatum, several studies have found evidence that the cortex may also be capable of regeneration under certain conditions (Magavi et al., 2000), including after ischemia, albeit with a low number of newly formed neurons (Kaplan, 1981)
GPR39 knockout mice display decreased CREB and BDNF levels in the hippocampus, but not in the frontal cortex [336]
selective NNMT inhibitors such as 5-Amino-1MQ are prominent tool compounds for target validation [2,8,9]
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