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The evidence suggests oxaloacetate may counteract fatigue through mechanisms that improve mitochondrial health, including the restoration of NAD+/NADH balance, enhancement of mitochondrial biogenesis, antioxidant action, reduction of glycolysis and lactate production, decreased NF-B activity and increased glucose uptake via AMPK activation

Cureus, 12(5), e8320

The anti-inflammatory effects appear synergistic with tissue healing properties, creating an optimal environment for regeneration

Grumbach MM (2002) The neuroendocrinology of human puberty revisited

Have you noticed that when your stomach is upset, you feel anxious or depressed