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MD simulation supports that the ZIL was concentrated near the surface of cellsZIL molecules, especially their carboxylates, electrostatically interact with the cell membrane, and consequently, ZIL is concentrated ~3 times more densely on the polar surface of the cell membrane than in the bulk state, even at 37 C (Fig
Howie AF et al
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It also plays a role in energy homeostasis and cellular metabolism
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