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Li QR, et al
2002, 283: L246-L255
At the 2.4 mg maintenance dose in clinical trials, approximately 44% of participants experienced nausea
However, a review paper in 2011 did not find enough evidence for the efficacy of this treatment due to shortcomings of these RCTs, as there were insufficient evidence and no data on functional status and quality of life to recommend these supplements as a treatment in chronic fatigue syndrome [50]
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