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Pantophlet, R., Wang, M., Aguilar-Sino, R

Similarly, IRE1 dysregulation has been observed in tauopathies, PrD, and HD, highlighting its role in neurotoxicity, whereas ATF6 dysfunction exacerbates protein aggregation and has been linked to FTD and tauopathies

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Theyre only eating when theyre hungry, and theyre stopping when theyre full." Jastreboff agreed that while obesity is "not an addiction," the "food noise," or impulse to eat, uses the same pathways in the brain