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Non-financial interests: ZM, SG, MP, and AM were Nestle Nutrition Institute Fellows

Still, these positive results can be enhanced when in combination with other drugs, such as metformin, which allows for an effective treatment plan with no increase in adverse symptoms usually seen with the treatment of semaglutide alone [121, 122, 125, 126]

Most practitioners initiate patients at 1 mL weekly during the first 4 to 8 weeks of GLP-1 therapy, then reassess tolerability and energy levels before advancing to 2 mL or increased frequency

At this point, researchers cannot say which explanationif anyis most important