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A 12-week multicenter randomized controlled trial provided strong evidence that for elderly people with sarcopenia or potential sarcopenia, the intervention of combined muscular-targeted oral nutritional supplements (rich in protein, HMB and vitamin D3) and structured exercise programs (including twin-weekly resistance training and interday chair exercises) compared with the control group It can more effectively improve the lean tissue of the limbs, skeletal muscle index, grip strength, walking speed, chair standing performance and quality of life [69]
doi: 10.1016/j.ghir.2015.08.002 152 OliveiraCRSalvatoriRBarreto-FilhoJARochaIEMariAPereiraRMet al
While not directly linked to GLP-1 production, its role in improving gut microbiome balance indirectly supports weight loss
People who are obese, based on their height and weight, have an amount of fat on their bodies representing a BMI of 30 or higher
Physiol Rev 94:739777
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