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Reported side effects are rare and mild: Localized irritation or redness at injection site
additional injections of vitamin B12 on the same day as pemetrexed or pralatrexate treatments as needed
NSAIDs NSAIDs inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby inflammation and pain
They also explain the safety question addressed further down this page: a peptide that drives new blood vessel growth and fibroblast migration is doing exactly what an injury needs, but the same pathway raises a legitimate question in anyone with active or undiagnosed cancer
Dose increases occur every 4 weeks to minimize gastrointestinal side effects [1]
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