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Numerous practice guidelines recommend multicomponent, evidence-based nutritional and behavioral therapy for adults with obesity, but use of such treatments with GLP-1s is not widespread [73]
Integrated Research Applications GLP-1S is used in research to examine incretin biology, receptor signaling, and metabolic control
Retatrutide Research# The pivotal Phase 2 trial (338 participants, NEJM 2023) showed 24.2% weight loss at 48 weeks
Theyre safe alongside most other therapies and medications
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