While most longevity interventions target single hallmarks of aging, like NAD+ boosters for mitochondrial support [2] or senolytics to clear senescent cells [3], Epitalons appeal lies in its multi-dimensional role in aging biology
Another neuronal-targeting peptide, Ten Eleven Translocation one (Tet-1), derived from tetanus toxin, binds to tri-sialo-ganglioside receptors located on the surface of motor neurons and has been used successfully to deliver therapeutic agents to neurons in several models (87)
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It is studied in research for its effects on increasing satellite cell proliferation, lowering cholesterol, inflammation reduction, and decrease of neuro-degeneration
References Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S